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Symphytum spp., comfrey
Summary

Formerly much valued as a herbal remedy but not now recommended for ingestion though application to the skin is, probably, harmless.
Family
Boraginaceae
Meaning of the Name
Symphytum
From the Greek, ‘sympho’, ‘to unite’ resulting from the plant’s
alleged ability to knit bones together.
caucasicum
From the Caucasus Mountains.
Common Names and Synonyms
comfrey

Symphytum spp., comfrey
How Poisonous, How Harmful?
Contains pyrrolidizine alkaloids including heliosupine and cynoglosine. The young leaves contain a highish concentration which is reduced as the leaves enlarge and age.
Trials have suggested that ingestion of 6kgs of comfrey would be necessary to cause severe liver damage. Even so, ingestion as a herbal remedy is not recommended. The same tests found that absorption through the skin is twenty to fifty times less efficient than ingestion so comfrey creams offered as herbal remedies are unlikely to cause any problems.
Incidents
The only known incidents relating to comfrey result from excessive use of herbal capsules or tea.
Folklore and Facts

John Gerard said of the benefits of the plant ‘The slimie
substance of the roote made in a posset of ale, and given to drinke
against the paine in the backe, gotten by any violent motion, as
wrestling, or over much use of women, doth in fower or five daies
perfectly cure the same, although the involuntarie flowing of the
seed in men be gotten thereby.’
‘Symphytum’ comes from a Greek word meaning ‘to knit together’. It
does contain allantoin, a substance which is said to increase cell
generation but the presence of pyrrolidizine alkaloids makes it
dangerous to ingest. Some sources suggest that even in ‘beneficial’
amounts, ingestion of comfrey for more than five days could cause
permanent liver damage in children.
